Academic League of Sickle Cell Disease

"Perceiving the world you live in is the first step in changing it." - André François

What is Sickle Cell Disease?
Sickle cell disease results from a genetic mutation that will modify hemoglobin, giving rise to a variant Hb called HbS. This hemoglobin has different characteristics from HbA and, when transporting oxygen, it can undergo irreversible changes that make the red blood cells take on an elongated shape, resembling a sickle, hence the name sickle cell. The sickle cell, then, has limitations in its functionality, the transport of oxygen and, as they are cells different from red blood cells that have hemoglobin A, they are destroyed by the body. People with sickle cell disease, due to this cell destruction, have anemia. Due to their shape, the cells can obstruct blood vessels, preventing the arrival of red blood cells in different parts of the body, which will trigger some characteristic symptoms of the disease, from bone pain to stroke, also causing a lack of oxygenation in the tissues, which will lead to tissue necrosis. Thus, it is extremely important that people with sickle cell disease have a multidisciplinary follow-up to improve their quality of life, as well as to reduce the hospitalization rate. 


What is LADF?
A Academic League of Sickle Cell Disease consists of a non-profit, non-religious, apolitical and unlimited duration entity, formed by a multidisciplinary team of academics, professors and professionals in the health area.


What is the purpose of the LADF?
A Academic League of Sickle Cell Disease it emerged with the intention of carrying out practical and theoretical activities, in addition to curricular activities, related to the subject, aimed at the development of research, teaching and extension, in order to bring knowledge to the population with this disease.


LADF website
www.ladf.med.br

LADF Email
info@ladf.med.br