MASTER IN DENTISTRY - OPEN ENROLLMENTS

RESEARCH LINES

ANDRÉ MALLMANN

andremallmann@uol.com.br

ARLEI CERQUEIRA

brandex@ig.com.br

BLANCA LILIANA TORRES LÉON

blalitole@hotmail.com

EMILENA MARIA C. XISTO LIMA

emilenalima@gmail.com

GABRIELA BOTELHO MARTINS

gbmartins@hotmail.com

GETÚLIO DA NOGUEIRA-FILHO

nogueirafilho@pq.cnpq.br

LUIZ GUSTAVO C. BASTOS

luizgcb@hotmail.com

MONICA GOLDEN

monicadourado@uol.com.br

PALOMA DIAS DA SILVA TELLES

p-telles@uol.com.br

SILVIA REGINA DE ALMEIDA REIS

srareis@uol.com.br

URBINO DA ROCHA TUNES

odontocoord@yahoo.com.br

VIVIANE MAIA B. DE OLIVEIRA

vikamaia@hotmail.com

1. DISEASES OF THE STOMATOGNATIC COMPLEX

This line of research seeks the clinical and histopathological study of lesions that affect the maxillofacial complex. It also aims to investigate clinical, surgical, epidemiological and histomorphological aspects of oral and systemic changes that affect the oral cavity. In this line of research, experimental, observational, descriptive and analytical works are developed, also using advanced laboratory techniques.

2. INFLAMMATION AND TISSUE REPAIR

The research line aims to study the inflammatory process and the different phases of the healing process involving dental specialties. Some components of the extracellular matrix, such as protein expression, is also evaluated, as well as the expression of myofibroblasts under the influence of several factors that interfere with healing. Animal and laboratory study models will be used through advanced histopathology techniques.

3. MOLECULAR BIOLOGY APPLIED TO DENTISTRY

This line of research studies the cellular and molecular mechanisms of oral physiological and pathological processes. The study of tissue bioengineering and dental pulp vascularization is important for understanding clinical findings and substantiating scientific evidence. It aims to use techniques in molecular biology (PCR, RT-PCR, Real Time RT-PCR, Flow cytometry, ELISA and other immunoassays) and cell cultures (monocytes, macrophages, odontoblasts, osteoblasts, fibroblasts, stem cells ) for the systematic development of experiments vitro e ex vivo that investigate molecular processes, from the production of cytokines to the genetic mapping of mRNA and DNA expression. Experimental studies include several dental specialties with an emphasis on Pediatric Dentistry, Periodontics and Immunology Applied to Dentistry.

4. PERIODONTAL MEDICINE

During the last decade, the study of Periodontics has extended its limits to encompass knowledge of the medical field as the need to analyze the patient as a whole becomes clearer every day. The relationship between periodontal disease and systemic disorders or conditions, such as smoking, cardiovascular disease, respiratory infections, diabetes, osteoporosis, stress, obesity, medications, among others, has been highlighted in the scientific literature. However, with each new publication, the questioning increases. Therefore, this line of research aims to develop clinical and laboratory works, of an epidemiological character, case-control and cross-sectional, to better evidence and characterize these relationships. Animal model studies can also be developed to clarify possible associations in the etiopathogenic process of systemic and periodontal diseases.

5. ETIOIMMUNOPATHOGENICS OF PERIODONTAL AND PERI-IMPLANT DISEASES

This line of research aims at studies related to the etiopathogenesis of periodontal and peri-implant diseases, analyzing microbiological, immunopathological and genetic variables in relation to the pathological profile of those diseases. The aim is clinical experimentation and animal model (mice, rats and rabbits), using microbiological (culture and PCR) and immunological techniques. It correlates risk factors, such as smoking and diabetes, to peri-implant diseases. Other objects of study are the chemical-mechanical control of supra and subgingival dental biofilm (mouthwashes, dentifrices and gels), bone repair around implants (animal models and longitudinal and transverse studies), and endo-perium lesions. It also studies periodontal diseases associated with systemic conditions.

6. BIOENGINEERING OF PERIODONTAL AND PERI-IMPLANT TISSUES

The development of bioengineering encompasses technological advances aimed at reconstructing lost periodontal structures, as well as gains in quantity and/or quality of alveolar bone for anchoring osseointegrated implants. Within this line of research works are developed on plastic surgery and periodontal regeneration (RTG) and peri-implant (ROG).

Mucogingival therapy involving procedures for the creation of keratinized mucosa, root coverage and edentulous ridge augmentation has extreme integration with restorative dentistry and especially with the growing aesthetic demand. Studies in this area will be clinical-surgical, case-control type, aiming to test techniques and biomaterials for efficiency, practicality and predictability of results. Periodontal regenerative therapy, on the other hand, remains a major challenge in periodontal therapy and the development of new biomaterials aims to allow for predictable and favorable procedures for the functional recovery of the periodontium and the alveolar and peri-implant bone. In this context, controlled clinical-surgical works testing therapies and biomaterials will be developed. This regenerative potential can also be evaluated in animal models that allow histological analysis of the healing process.

7. RESTORATION BIOMATERIALS IN ORAL REHABILITATION

The materials and restorative techniques used in Dentistry, in rehabilitation disciplines, have evolved rapidly, making the options of choice in an increasingly complex rehabilitation work. Despite constant researches found in the literature, there are few scientific works on the techniques and materials recently introduced. It is also observed that the works developed in oral rehabilitation do not use the techniques and materials recently launched in the dental market. Thus, the objective of this line of research is to explore new materials that are used from prevention to completion of a rehabilitative treatment, mainly regarding their physical and biological properties. It is also an objective to carry out clinical and laboratory studies that analyze the use of these materials in rehabilitation treatments in partially or totally edentulous patients, thus bringing new possibilities for restorative solutions.