"Perceiving the world you live in is the first step in changing it." - André François

What is Sickle Cell Disease?
Sickle cell disease results from a genetic mutation that will modify hemoglobin, giving rise to a variant Hb called HbS. This hemoglobin has different characteristics from HbA and, when transporting oxygen, it can undergo irreversible changes that make the red blood cells take on an elongated shape, resembling a sickle, hence the name sickle cell. The sickle cell, then, has limitations in its functionality, the transport of oxygen and, as they are cells different from red blood cells that have hemoglobin A, they are destroyed by the body. People with sickle cell disease, due to this cell destruction, have anemia. Due to their shape, the cells can obstruct blood vessels, preventing the arrival of red blood cells in different parts of the body, which will trigger some characteristic symptoms of the disease, from bone pain to stroke, also causing a lack of oxygenation in the tissues, which will lead to tissue necrosis. Thus, it is extremely important that people with sickle cell disease have a multidisciplinary follow-up to improve their quality of life, as well as to reduce the hospitalization rate. 


What is LADF?
A Liga Acadêmica da Doença Falciforme consiste em uma entidade sem fins lucrativos, não religiosos, apolíticos e com duração ilimitada, formada por uma equipe multiprofissional de acadêmicos, docentes e profissionais da área de saúde.


What is the purpose of the LADF?
A Liga Acadêmica da Doença Falciforme surgiu com a pretensão de realizar atividades práticas e teóricas, além das curriculares, referentes ao tema, voltadas para o desenvolvimento da pesquisa, ensino e extensão, a fim de levar o conhecimento para a população portadora dessa doença.


LADF website
www.ladf.med.br

LADF Email
info@ladf.med.br